Detalhe da pesquisa
1.
Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses.
Cell
; 186(25): 5606-5619.e24, 2023 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38065081
2.
PANTHER: AZD8931, inhibitor of EGFR, ERBB2 and ERBB3 signalling, combined with FOLFIRI: a Phase I/II study to determine the importance of schedule and activity in colorectal cancer.
Br J Cancer
; 128(2): 245-254, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36352028
3.
Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer.
N Engl J Med
; 381(4): 317-327, 2019 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31157963
4.
T cell-inflamed gene expression profile and PD-L1 expression and pembrolizumab efficacy in advanced esophageal cancer.
Future Oncol
; 2022 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35852104
5.
Effects of N-terminus modified Hx-amides on DNA binding affinity, sequence specificity, cellular uptake, and gene expression.
Bioorg Med Chem Lett
; 47: 128158, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34058343
6.
Stress-specific p38 MAPK activation is sufficient to drive EGFR endocytosis but not its nuclear translocation.
J Cell Sci
; 130(15): 2481-2490, 2017 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28646091
7.
Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer.
Gut
; 67(1): 179-193, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29233930
8.
Multiple criteria decision analysis in the context of health technology assessment: a simulation exercise on metastatic colorectal cancer with multiple stakeholders in the English setting.
BMC Med Inform Decis Mak
; 17(1): 149, 2017 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29073892
9.
Molecular effects of Lapatinib in the treatment of HER2 overexpressing oesophago-gastric adenocarcinoma.
Br J Cancer
; 113(9): 1305-12, 2015 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26484410
10.
Comprehensive Examination of Cholangiocarcinoma Patients Treated with Novel Targeted Therapies after Extended Molecular Profiling on Liquid Biopsies.
Cancers (Basel)
; 16(4)2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38398088
11.
Evidence for different mechanisms of 'unhooking' for melphalan and cisplatin-induced DNA interstrand cross-links in vitro and in clinical acquired resistant tumour samples.
BMC Cancer
; 12: 436, 2012 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23020514
12.
The role of PARP inhibitors in gastrointestinal cancers.
Crit Rev Oncol Hematol
; 171: 103621, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35124199
13.
Overall Survival Results From the POLO Trial: A Phase III Study of Active Maintenance Olaparib Versus Placebo for Germline BRCA-Mutated Metastatic Pancreatic Cancer.
J Clin Oncol
; 40(34): 3929-3939, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35834777
14.
Drug delivery, biodistribution and anti-EGFR activity: theragnostic nanoparticles for simultaneous in vivo delivery of tyrosine kinase inhibitors and kinase activity biosensors.
Nanoscale
; 13(44): 18520-18535, 2021 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34730152
15.
Efficacy of Pembrolizumab Monotherapy for Advanced Gastric/Gastroesophageal Junction Cancer with Programmed Death Ligand 1 Combined Positive Score ≥10.
Clin Cancer Res
; 27(7): 1923-1931, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33446564
16.
Targeting the ICB2 site of the topoisomerase IIalpha promoter with a formamido-pyrrole-imidazole-pyrrole H-pin polyamide.
Bioorg Med Chem
; 18(15): 5553-61, 2010 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20615712
17.
Phase I study of sequence-selective minor groove DNA binding agent SJG-136 in patients with advanced solid tumors.
Clin Cancer Res
; 15(6): 2140-7, 2009 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19276288
18.
Multimodal Treatment in Metastatic Colorectal Cancer (mCRC) Improves Outcomes-The University College London Hospital (UCLH) Experience.
Cancers (Basel)
; 12(12)2020 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33261002
19.
Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.
Sci Rep
; 10(1): 663, 2020 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31959764
20.
COVID-19 in cancer patients on systemic anti-cancer therapies: outcomes from the CAPITOL (COVID-19 Cancer PatIenT Outcomes in North London) cohort study.
Ther Adv Med Oncol
; 12: 1758835920971147, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33178336